Molecular hydrogen (H2) is a versatile therapeutic agent. Inhaling H2 gas is reported to be safe and has positive effects on a range of diseases, including Alzheimer's disease (AD). Here, we studied community adults of different ages inhaling H2 gas for 4 weeks. Fifty-four participants, three of whom dropped out (5%), were screened and enrolled. Selected subjects are treated as a single group without randomization. We assessed the association between total and classified white blood cell (WBC) counts at the individual level and the risk of AD after 4 weeks of hydrogen inhalation. The total number of WBC and the classified WBC count were not adversely affected after H2 gas inhalation therapy, indicating that it was well tolerated and that hydrogen inhalation was safe. Studies of markers of oxidative stress such as reactive oxygen species and nitric oxide have shown that their levels drop after hydrogen inhalation therapy. In addition, the evaluation of dementia related biomarkers, such as β-site APP lyase 1 (BACE-1), beta-amyloid protein (Aβ), brain-derived neurotrophic factor (BDNF), vascular endothelial growth factor A (VEGF-A), T-TAU, Monocyte chemoattractant protein-1 (MCP-1) and inflammatory cytokine (interleukin-6), results showed that in most cases, their cognitive status improved significantly after hydrogen inhalation treatment. Overall, our results suggest that H2 inhalation may ameliorate cognitive dysfunction in adults living in communities of different ages and that hydrogen is a good candidate for AD treatment.
We often hear some people who are very serious about the hydrogen therapy, and serious here means that it is used every day, for a long time every day, often combined with inhalation and drinking, and the inhalation time is relatively long every day, and the use of hydrogen is also relatively long. This kind of serious use of hydrogen, the magic effect is often more. For example, if there is long-term hypertension, the blood pressure will return to normal, and the drug will be gradually reduced or even stopped. Parkinson's disease goes from being unable to take care of oneself to being able to take care of oneself. Cognitive function is significantly improved in patients with senile dementia. The past memory decline of ordinary middle-aged and elderly people has been significantly improved. Rosy complexion becomes younger, age spots gradually fade. Sleep quality improved significantly, and energy became more abundant. Unfortunately, this is all amazing, but there is no good research evidence. Professor Korea Lee's recent research on residents in healthy communities provides us with a very good research paradigm, and we should actively promote the observation and research of the above various effects in social populations, which is also valuable for promoting the transformation and application of hydrogen health medicine.
